Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCL3 | P20749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886348 | 0.80 | KMT2A (0.48) | L3MBTL1ALDH1A1KMT2ATHRBSMN1; SMN2 | |
| SCHEMBL4893712 | 0.79 | MEN1 (0.45) | L3MBTL1ALDH1A1CHIAKMT2ATHRB | |
| SCHEMBL4892547 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KMT2AHPGDLMNASMN1; SMN2 | |
| SCHEMBL4882730 | 0.69 | THRB (0.42) | ALDH1A1KMT2ATHRBMAPTGAA | |
| SCHEMBL4883922 | 0.68 | RAB9A (0.50) | ALDH1A1KMT2ATHRBMAPTHPGD | |
| SCHEMBL4892647 | 0.67 | KDM4E (0.45) | L3MBTL1ALDH1A1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4896093 | 0.66 | KMT2A (0.46) | L3MBTL1ALDH1A1KMT2AOPRK1HPGD | |
| SCHEMBL18394741 | 0.66 | CHIA (0.54) | ALDH1A1CHIAKMT2AP2RX7SMN1; SMN2 | |
| SCHEMBL16105029 | 0.66 | OPRK1 (0.61) | ALDH1A1MAPTOPRK1LMNA | |
| SCHEMBL29574622 | 0.64 | KMT2A (0.65) | L3MBTL1ALDH1A1CHIAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | L3MBTL1 3221/4885ALDH1A1 276/4885CHIA 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.