Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL29493216 | 1.00 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL106190 | 1.00 | — | — | |
| Propionic Acid SCHEMBL21798886 | 0.96 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL2070238 | 0.96 | — | — | |
| Propionic Acid SCHEMBL11050406 | 0.96 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL11208525 | 0.96 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL11214158 | 0.96 | — | — | |
| Propionic Acid SCHEMBL28884837 | 0.93 | — | — | |
| Oxalic Acid SCHEMBL6685439 | 0.93 | FFAR3 (0.47) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL4813110 | 0.92 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714958-A1 | COMBINED THERAPY OF PHOTODYNAMIC THERAPY AND IMMUNE CHECKPOINT INHIBITOR | Shanghai Guangsheng Biopharmaceutical Co., Ltd (CN) | 2026-03-25 | — | — | EP | claimed |
| US-20260069696-A1 | Combined therapy of photodynamic therapy and immune checkpoint inhibitor | Shanghai Guang Sheng Pharmaceutical Co., Ltd. (CN) | 2026-03-12 | — | — | US | claimed |
| WO-2025082342-A1 | INTEGRATED PHOTODYNAMIC DIAGNOSIS AND TREATMENT METHOD | 上海光声制药有限公司 | 2025-04-24 | — | — | WO | claimed |
| CN-119856902-A | Photodynamic diagnosis and treatment integrated method | 上海光声制药有限公司 | 2025-04-22 | — | — | CN | claimed |
| US-20250064743-A1 | TREPROSTINIL DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | UNITED THERAPEUTICS CORPORATION (US) | 2025-02-27 | — | — | US | claimed |
| WO-2024240023-A1 | COMBINED THERAPY OF PHOTODYNAMIC THERAPY AND IMMUNE CHECKPOINT INHIBITOR | 上海光声制药有限公司 | 2024-11-28 | — | — | WO | claimed |
| CN-119015410-A | Combination therapy with photodynamic therapy and immune checkpoint inhibitors | 上海光声制药有限公司 | 2024-11-26 | — | — | CN | claimed |
| US-20220280430-A1 | TREPROSTINIL DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | UNITED THERAPEUTICS CORPORATION (US) | 2022-09-08 | — | — | US | claimed |
| US-RE32416-E | ACID PROPIONATE SALT IN BREAD | BP CHEMICALS LIMITED (GB) | 1987-05-12 | — | — | US | claimed |
| EP-0123416-A1 | Method of producing solid potassium dipropionate | VERDUGT B.V. (NL) | 1984-10-31 | — | — | EP | claimed |
| EP-0112080-A1 | Compound animal feedstuffs | BP Chemicals Limited (GB) | 1984-06-27 | — | — | EP | claimed |
| EP-0032807-B1 | DIPOTASSIUM PENTAPROPIONATE AND METHOD OF PREPARING THE SAME | BP Chemicals Limited (GB) | 1983-01-19 | — | — | EP | claimed |
| EP-0032807-A1 | Dipotassium pentapropionate and method of preparing the same | BP Chemicals Limited (GB) | 1981-07-29 | — | — | EP | claimed |
| US-4112122-A | OF FOODS, METAL PROPIONATE | BP CHEMICALS LIMITED (GB) | 1978-09-05 | — | — | US | claimed |
| JP-59181236-A | — | — | None | — | — | JP | disclosed |
| EP-4714958-A1 | COMBINED THERAPY OF PHOTODYNAMIC THERAPY AND IMMUNE CHECKPOINT INHIBITOR | Shanghai Guangsheng Biopharmaceutical Co., Ltd (CN) | 2026-03-25 | — | — | EP | disclosed |
| US-20260069696-A1 | Combined therapy of photodynamic therapy and immune checkpoint inhibitor | Shanghai Guang Sheng Pharmaceutical Co., Ltd. (CN) | 2026-03-12 | — | — | US | disclosed |
| EP-0032807-A1 | Dipotassium pentapropionate and method of preparing the same | BP Chemicals Limited (GB) | 1981-07-29 | — | — | EP | disclosed |
| EP-0032807-A1 | Dipotassium pentapropionate and method of preparing the same | BP Chemicals Limited (GB) | 1981-07-29 | — | — | EP | disclosed |
| US-4112122-A | OF FOODS, METAL PROPIONATE | BP CHEMICALS LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280430-A1 | TREPROSTINIL DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | TREH, TKT, TPP2 | FFAR3 489/4885HDAC3 942/4885HDAC1 488/4885 |
| US-20250064743-A1 | TREPROSTINIL DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | TREH, THPO, TPP2 | FFAR3 1177/4885HDAC3 981/4885HDAC1 833/4885 |
| US-20260069696-A1 | Combined therapy of photodynamic therapy and immune checkpoint inhibitor | PDCD1, PDCD10, CD274 | FFAR3 4651/4885HDAC3 1947/4885HDAC1 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.