Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.38 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891786 | 0.91 | ALDH1A1 (0.42) | MAPTMALT1TRPC3TRPC1STIM1 | |
| SCHEMBL4885880 | 0.84 | CNR1 (0.39) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4786438 | 0.82 | CNR1 (0.43) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL3441956 | 0.82 | ALDH1A1 (0.45) | MAPTTP53THRBMALT1KDM4E | |
| SCHEMBL3441757 | 0.76 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL4894672 | 0.76 | MAPK14 (0.34) | MAPTKDM4ELMNAHTTMET | |
| SCHEMBL4886940 | 0.75 | MEN1 (0.35) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL4897672 | 0.75 | FFAR2 (0.40) | MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL2856449 | 0.74 | MAPT (0.50) | MAPTTP53THRBMALT1TRPC3 | |
| SCHEMBL14020621 | 0.72 | KDM4E (0.34) | MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262064-A1 | Novel Compounds For The Treatment Of GI Disorders 682 | ASTRAZENECA AB (SE) | 2008-10-23 | — | — | US | claimed |
| US-20080262064-A1 | Novel Compounds For The Treatment Of GI Disorders 682 | ASTRAZENECA AB (SE) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262064-A1 | Novel Compounds For The Treatment Of GI Disorders 682 | GABRB2, GABRA2, GABBR2 | MAPT 1814/4885TP53 4858/4885THRB 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.