Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638491 | 1.00 | NAMPT (0.56) | NAMPTALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL1412504 | 1.00 | NAMPT (0.56) | NAMPTALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL126610 | 1.00 | NAMPT (0.56) | NAMPTALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL11145541 | 0.80 | NPC1 (0.54) | ALDH1A1KDM4ECYP2C19NPC1RAB9A | |
| SCHEMBL18642083 | 0.78 | MAPT (0.47) | NAMPTALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL31234028 | 0.77 | SMN1; SMN2 (0.67) | NAMPTALDH1A1KDM4ECYP2C19NPC1 | |
| SCHEMBL11833345 | 0.76 | LMNA (0.79) | ALDH1A1KDM4ECYP2C19CYP1A2NPC1 | |
| SCHEMBL20432655 | 0.76 | FAAH (0.65) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL20420962 | 0.75 | FAAH (0.51) | KDM4ENPC1RAB9ATP53MAPT | |
| SCHEMBL22635896 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746505-B1 | COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME | DOW SILICONES CORP (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-3906245-B1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20240124709-A1 | COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME | DOW GLOBAL TECHNOLOGIES LLC | 2024-04-18 | — | — | US | disclosed |
| EP-3645640-B1 | SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME | DOW SILICONES CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11884821-B2 | Composition, polymer composite article formed therewith, and method of preparing same | DOW SILICONES CORPORATION (US) | 2024-01-30 | — | — | US | disclosed |
| US-11807775-B2 | Silicone-organic copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11760841-B2 | Silicone-polycarbonate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3898779-B1 | SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-3898781-B1 | SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20220064482-A1 | SILICONE-ORGANIC COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-10 | — | — | US | disclosed |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140171547-A1 | Bismuth Containing Complex and Condensation Reaction Curable Compositions and Methods for the Preparation and Use of the Compositions | DOW CORNING CORPORATION | 2014-06-19 | — | — | US | disclosed |
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | DOW CORNING CORPORATION (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140100347-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-04-10 | — | — | US | disclosed |
| US-20140039089-A1 | Compositions Containing Phosphonate Catalysts And Methods For The Preparation And Use Of The Compositions | DOW CORNING CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140018467-A1 | COMPOSITIONS CONTAINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2014-01-16 | — | — | US | disclosed |
| US-20080118734-A1 | Coating Compositions | DOW CORNING IRELAND LTD. (IE) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | HIRA, HIRIP3, CROCC | NAMPT 2442/4885ALDH1A1 1659/4885KDM4E 4246/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | NAMPT 1449/4885ALDH1A1 2299/4885KDM4E 4572/4885 |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ITGA1, TMT1A, ITGA2 | NAMPT 3113/4885ALDH1A1 2501/4885KDM4E 4263/4885 |
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | ZRANB2, ZKSCAN2, SLC39A3 | NAMPT 2758/4885ALDH1A1 1749/4885KDM4E 4455/4885 |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, HACL2, CROCC | NAMPT 2965/4885ALDH1A1 1409/4885KDM4E 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.