Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906644 | 0.88 | PSEN1 (0.43) | CYP1A2CTSLCTSBCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL4899189 | 0.87 | PSEN1 (0.43) | CYP1A2CTSLCTSBCYP3A4CYP2C9 | |
| SCHEMBL14258733 | 0.81 | SCN9A (0.43) | CYP1A2CYP3A4CYP2C19KMOALDH1A1 | |
| Hydrochloric Acid SCHEMBL4904250 | 0.80 | SCN9A (0.42) | CYP1A2CYP3A4CYP2C19KMOALDH1A1 | |
| SCHEMBL4909219 | 0.76 | PSEN1 (0.43) | CYP3A4KIF11NR3C2 | |
| SCHEMBL4904069 | 0.75 | PSEN1 (0.42) | CYP3A4KIF11GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL4908124 | 0.75 | PSEN1 (0.42) | CYP3A4KIF11NR3C2 | |
| SCHEMBL4726259 | 0.74 | CYP1A2 (0.39) | CYP1A2CTSLCTSBCYP3A4CYP2C9 | |
| SCHEMBL10254409 | 0.73 | ADRB2 (0.56) | CYP3A4KCNH2ALDH1A1GAATLR7 | |
| SCHEMBL17293841 | 0.72 | THRA (0.43) | KIF11KMOALDH1A1KDM4EBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058391-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-03-06 | — | — | US | disclosed |
| US-20080058391-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-03-06 | — | — | US | disclosed |
| US-20080058391-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058391-A1 | NOVEL COMPOUNDS | HCN3, KCNN3, HCN4 | CYP1A2 1926/4885CTSL 3296/4885CTSB 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.