SCHEMBL490498

SCHEMBL490498

COC(OC)(OC(=O)CC(=O)OO)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.43
CES1 P23141 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
POLB P06746 2/20 0.36
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733637 0.87 KCNN4 (0.46) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL784057 0.81 OPRM1 (0.45) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL784815 0.79 CES1 (0.41) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL31189243 0.78 CES1 (0.36) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL2341249 0.77 CES1 (0.48) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL784813 0.75 CES1 (0.47) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL19973037 0.74 MAPT (0.47) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL784070 0.73 TSHR (0.53) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL3880018 0.72 ALDH1A1 (0.52) KCNN4CES1CYP2C19HIF1APOLB
SCHEMBL783660 0.71 KCNN4 (0.47) KCNN4CES1CYP2C19HIF1APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3818973-B1 WATER-RESISTANT SOLAR COMPOSITION WITH HIGH TRIAZINE CONTENT THOREL JEAN NOEL (FR) 2024-02-07 EP claimed
EP-3818973-A1 WATER-RESISTANT SOLAR COMPOSITION WITH HIGH TRIAZINE CONTENT Thorel, Jean-Noël (FR) 2021-05-12 EP claimed
EP-2323613-B1 COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME ELC MAN LLC (US) 2016-11-30 EP claimed
EP-2323613-A2 COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME ELC Management LLC (US) 2011-05-25 EP claimed
WO-2010019413-A2 COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME ELC MANAGEMENT LLC (US) 2010-02-18 WO claimed
US-20100040696-A1 Composite Particles Having An Antioxidant-Based Protective System, And Topical Compositions Comprising The Same ELC MANAGEMENT LLC 2010-02-18 US claimed
WO-2026087604-A1 ECOBIOLOGICAL COMPOSITION COMPRISING ENVIRONMENTALLY FRIENDLY SUN PROTECTION BOOSTERS NAOS INSTITUTE OF LIFE SCIENCE (FR) 2026-04-30 WO disclosed
US-20250275904-A1 ANTI-SUN COSMETIC COMPOSITION CONTAINING MYCOSPORINE-LIKE AMINO ACIDS Thorel, Jean-Noël (FR) 2025-09-04 US disclosed
WO-2025088285-A1 ECOBIOLOGICAL TOPICAL COMPOSITION FOR TREATING SKIN REDNESS AND DISCOMFORT NAOS INSTITUTE OF LIFE SCIENCE (FR) 2025-05-01 WO disclosed
WO-2024218461-A1 ECOBIOLOGICAL COSMETIC COMPOSITION CAPABLE OF PROMOTING SKIN WOUND HEALING NAOS INSTITUTE OF LIFE SCIENCE (FR) 2024-10-24 WO disclosed
EP-4366686-A1 ANTI-SUN COSMETIC COMPOSITION CONTAINING MYCOSPORINE-LIKE AMINO ACIDS NAOS Institute of Life Science (FR) 2024-05-15 EP disclosed
EP-3818973-B1 WATER-RESISTANT SOLAR COMPOSITION WITH HIGH TRIAZINE CONTENT THOREL JEAN NOEL (FR) 2024-02-07 EP disclosed
EP-4234040-A2 COSMETIC COMPOSITION WITH HIGH CONTENT OF TRIAZINE DERIVATIVE SOLAR FILTERS Thorel, Jean-Noël (FR) 2023-08-30 EP disclosed
EP-2323613-A2 COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME ELC Management LLC (US) 2011-05-25 EP disclosed
WO-2010019413-A2 COMPOSITE PARTICLES HAVING AN ANTIOXIDANT-BASED PROTECTIVE SYSTEM, AND TOPICAL COMPOSITIONS COMPRISING THE SAME ELC MANAGEMENT LLC (US) 2010-02-18 WO disclosed
US-20100040696-A1 Composite Particles Having An Antioxidant-Based Protective System, And Topical Compositions Comprising The Same ELC MANAGEMENT LLC 2010-02-18 US disclosed
US-20100034893-A1 PARTICULATE UV PROTECTION AGENT MERCK PATENT GMBH (DE) 2010-02-11 US disclosed
EP-2125115-A2 PARTICULATE UV PROTECTION AGENT Merck Patent GmbH (DE) 2009-12-02 EP disclosed
WO-2008092590-A2 PARTICULATE UV PROTECTION AGENT MERCK PATENT GMBH (DE) 2008-08-07 WO disclosed
US-20080152603-A1 Antioxidants SUSONITY Commercial GmbH (DE) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275904-A1 ANTI-SUN COSMETIC COMPOSITION CONTAINING MYCOSPORINE-LIKE AMINO ACIDS CUTA, MYC, XPA KCNN4 4268/4885CES1 4392/4885CYP2C19 1870/4885
US-20080152603-A1 Antioxidants GPX4, GPX1, CAT KCNN4 2854/4885CES1 1034/4885CYP2C19 410/4885
US-20100034893-A1 PARTICULATE UV PROTECTION AGENT SOD1, SOD3, UNG KCNN4 2364/4885CES1 4742/4885CYP2C19 1229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.