O,P'-Dde (1,1-(O,P'-Dichlorodiphenyl)-2,2 Dichloroethene)

O,P'-Dde (1,1-(O,P'-Dichlorodiphenyl)-2,2 Dichloroethene)

SCHEMBL4906413

ClC(Cl)=C(c1ccc(Cl)cc1)c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
CYP3A4 P08684 1/20 0.61
MAPK1 P28482 1/20 0.61
ATM Q13315 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
RAB9A P51151 2/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
NR4A1 P22736 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MGLL Q99685 1/20 0.42
KMT2A Q03164 2/20 0.40
ALOX15 P16050 1/20 0.40
FLT1 P17948 1/20 0.40
FLT4 P35916 1/20 0.40
KDR P35968 1/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199572 0.83 CES2 (0.54) TSHRCYP3A4MAPK1ATML3MBTL1
SCHEMBL7772998 0.79 TSHR (0.81) TSHRCYP3A4MAPK1ATML3MBTL1
Dichlorodiphenyldichloroethylene SCHEMBL177472 0.78 TSHR (1.00) TSHRCYP3A4MAPK1ATML3MBTL1
SCHEMBL3138767 0.75 CES2 (0.54) TSHRL3MBTL1RAB9AHPGDSMN1; SMN2
4-Chloro-Benzoic Acid SCHEMBL6852257 0.74 ALDH1A1 (0.73) TSHRCYP3A4RAB9AHPGDSMN1; SMN2
SCHEMBL2933370 0.73 RAB9A (0.46) RAB9AHPGDSMN1; SMN2CES2CES1
SCHEMBL29989484 0.73 NR4A1 (0.69) MAPK1RAB9AHPGDSMN1; SMN2CES2
SCHEMBL2991958 0.73 NR4A1 (0.69) MAPK1RAB9AHPGDSMN1; SMN2CES2
SCHEMBL9869117 0.73 CES2 (0.56) TSHRRAB9AHPGDSMN1; SMN2CES2
SCHEMBL10808749 0.72 CES2 (0.72) RAB9AHPGDSMN1; SMN2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113495108-B Method for simultaneously detecting 63 persistent organic pollutants in soil 生态环境部华南环境科学研究所 2023-07-28 CN claimed
CN-105801019-A Durable constructional exterior-wall paint 青岛锦涟鑫商贸有限公司 2016-07-27 CN claimed
CN-104059416-B White-out agent environmental protection fire retarding agent CHUZHOU SMET COMPOUND MATERIALS CO., LTD. (CN) 2015-12-09 CN claimed
EP-0409689-B1 A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol ATOCHEM ELF SA (FR) 1995-03-22 EP claimed
US-5081319-A Isolation and purification SOCIEDAD ESPANOLA DE DESARROLLOS QUIMICOS S.A. (ES) 1992-01-14 US claimed
EP-0409689-A2 A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol ELF ATOCHEM S.A. (FR) 1991-01-23 EP claimed
US-12628855-B2 Cannabis plant residue and use thereof ALTHEDA WELLNESS INNOVATION INC. (CA) 2026-05-19 US disclosed
CN-122033237-A Vulcanized nano zero-valent iron and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20260097972-A9 WATER TREATMENT AND DESALINATION SYLVAN SOURCE INC (US) 2026-04-09 US disclosed
EP-4644553-A9 NON-NUCLEIC ACID TARGET DETECTION METHOD BASED ON SPLIT CAS PROTEIN AND USE THEREOF Shanghai Tolo Biotechnology Company Limited (CN) 2025-12-17 EP disclosed
EP-4644553-A1 NON-NUCLEIC ACID TARGET DETECTION METHOD BASED ON SPLIT CAS PROTEIN AND USE THEREOF Shanghai Tolo Biotechnology Company Limited (CN) 2025-11-05 EP disclosed
US-20250281926-A1 SAMPLE MANIPULATION AND ASSAY WITH RAPID TEMPERATURE CHANGE ESSENLIX CORPORATION (US) 2025-09-11 US disclosed
US-20250171332-A1 WATER TREATMENT AND DESALINATION SYLVAN SOURCE, INC. 2025-05-29 US disclosed
EP-0248954-B1 PROCESS FOR REDUCING THE AMOUNT OF DDT-RELATED IMPURITIES IN 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLORO-ETHANOL ROHM AND HAAS COMPANY (US) 1992-04-01 EP disclosed
US-5081319-A Isolation and purification SOCIEDAD ESPANOLA DE DESARROLLOS QUIMICOS S.A. (ES) 1992-01-14 US disclosed
EP-0460977-A1 Process for reducing the amount of DDT-related impurities in 1,1-bis (chlorophenyl)-2,2,2-trichloroethanol ROHM AND HAAS COMPANY (US) 1991-12-11 EP disclosed
EP-0409689-A2 A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol ELF ATOCHEM S.A. (FR) 1991-01-23 EP disclosed
US-4960945-A Process for the production of halobenzophenone derivatives KUREHA KAGAKU KOGYO K.K. (JP) 1990-10-02 US disclosed
EP-0248954-A1 Process for reducing the amount of DDT-related impurities in 1,1-bis(chlorophenyl)-2,2,2-trichloro-ethanol ROHM AND HAAS COMPANY (US) 1987-12-16 EP disclosed
US-4705902-A DDTR-free 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol ROHM AND HAAS COMPANY (US) 1987-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097972-A9 WATER TREATMENT AND DESALINATION AS3MT, TBCD, HSPE1 TSHR 1323/4885CYP3A4 1614/4885MAPK1 1571/4885
US-12628855-B2 Cannabis plant residue and use thereof CNR1, CNR2, CRH TSHR 2367/4885CYP3A4 1679/4885MAPK1 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.