SCHEMBL490676

SCHEMBL490676

CCCCCCCCCCCO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.65
▸ LGALS8 O00214 1/20 0.60
▸ LGALS3 P17931 1/20 0.60
▸ LGALS4 P56470 1/20 0.60
▸ CETP P11597 1/20 0.54
▸ GJB2 P29033 1/20 0.52
▸ GBA1 P04062 1/20 0.51
▸ IGF2R P11717 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2443026 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2443027 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL4106706 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2448130 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL25480871 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2447144 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL23016771 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL22691938 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL22111992 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL21067398 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018204669-A1 INTRAVENOUS IMMUNOGLOBULIN COMPOSITIONS SPECIFIC FOR RESPIRATORY SYNCYTIAL VIRUS AND METHODS OF MAKING AND USING THE SAME NANOBIO CORPORATION (US) 2018-11-08 — — WO claimed
EP-2278997-A1 NANOEMULSION INFLUENZA VACCINE Nanobio Corporation (US) 2011-02-02 — — EP claimed
US-20100172845-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIAL INFECTIONS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-07-08 — — US claimed
WO-2009131995-A1 NANOEMULSION INFLUENZA VACCINE NANOBIO CORPORATION (US) 2009-10-29 — — WO claimed
US-20080269163-A1 Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis UNIVERSITY OF FUKUI (JP) 2008-10-30 — — US claimed
EP-1814559-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-08-08 — — EP claimed
WO-2006045050-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2006-04-27 — — WO claimed
EP-0908172-A1 Cosmetic and dermatological photoprotective compositions in the form of O/W emulsions containing hydrophobic inorganic micropigments and hydrophilic surfactants Beiersdorf Aktiengesellschaft (DE) 1999-04-14 — — EP claimed
EP-2259768-B1 COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE MERCK PATENT GMBH (DE) 2019-05-22 — — EP disclosed
US-10278911-B2 Compositions containing cyclic peptides and methods of use MERCK PATENT GMBH (DE) 2019-05-07 — — US disclosed
EP-2553026-B1 METAL OXIDE PARTICLES AFTER-TREATED WITH ORGANIC PHOSPHORUS COMPOUNDS MERCK PATENT GMBH (DE) 2018-03-28 — — EP disclosed
EP-3218479-A1 METHOD FOR IDENTIFICATION OF MOLECULES WITH DESIRED CHARACTERISTICS Nanocore ApS (DK) 2017-09-20 — — EP disclosed
US-9700501-B2 Use of indole compounds as a cosmetic MERCK PATENT GMBH (DE) 2017-07-11 — — US disclosed
US-20170105910-A1 UV FILTER CAPSULE BASF SE (DE) 2017-04-20 — — US disclosed
EP-1250331-A1 FORMULATION FOR PROTECTION AGAINST OXIDATIVE STRESS CONTAINING BENZOFURANONE DERIVATIVES MERCK PATENT GmbH (DE) 2002-10-23 — — EP disclosed
WO-2001055128-A1 FORMULATION FOR PROTECTION AGAINST OXIDATIVE STRESS CONTAINING BENZOFURANONE DERIVATIVES MERCK PATENT GMBH (DE) 2001-08-02 — — WO disclosed
EP-1109539-A1 NANOGEL NETWORKS AND BIOLOGICAL AGENT COMPOSITION THEREOF SUPRATEK PHARMA, INC. (CA) 2001-06-27 — — EP disclosed
WO-2000058503-A2 IMPROVED METHOD FOR DETECTING MICRO-ORGANISMS ZETATRONICS LIMITED (GB) 2000-10-05 — — WO disclosed
WO-2000013677-A1 NANOGEL NETWORKS AND BIOLOGICAL AGENT COMPOSITION THEREOF SUPRATEK PHARMA, INC. (CA) 2000-03-16 — — WO disclosed
EP-0908172-A1 Cosmetic and dermatological photoprotective compositions in the form of O/W emulsions containing hydrophobic inorganic micropigments and hydrophilic surfactants Beiersdorf Aktiengesellschaft (DE) 1999-04-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170105910-A1 UV FILTER CAPSULE UROD, MITF, NISCH MAPK1 4145/4885LGALS8 3846/4885LGALS3 4323/4885
US-10278911-B2 Compositions containing cyclic peptides and methods of use CUTA, NGLY1, CALCA MAPK1 3603/4885LGALS8 653/4885LGALS3 355/4885
US-20080269163-A1 Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis GZMB, RNASE1, CASP3 MAPK1 4514/4885LGALS8 124/4885LGALS3 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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