Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907245 | 1.00 | TSHR (0.51) | TSHRCCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4910090 | 0.81 | ALDH1A1 (0.47) | CCR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4913350 | 0.80 | MAPT (0.42) | TSHRCCR2MAPTPIN1MEN1 | |
| SCHEMBL4913344 | 0.80 | MAPT (0.42) | TSHRCCR2MAPTPIN1MEN1 | |
| SCHEMBL4912883 | 0.78 | PIN1 (0.38) | TSHRCCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4912892 | 0.78 | PIN1 (0.38) | TSHRCCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4912851 | 0.77 | CCR2 (0.54) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL10222852 | 0.77 | PIN1 (0.43) | TSHRMAPTGFERPIN1MEN1 | |
| SCHEMBL4910462 | 0.76 | ALDH1A1 (0.55) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL307028 | 0.76 | PIN1 (0.65) | MAPTGFERPIN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | TSHR 861/4885CCR2 1/4885CYP1A2 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.