Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913350 | 1.00 | MAPT (0.42) | MAPTPTGER4CCR2PIN1POLB | |
| SCHEMBL4912883 | 0.83 | PIN1 (0.38) | MAPTPTGER4CCR2PIN1POLB | |
| SCHEMBL4912892 | 0.83 | PIN1 (0.38) | MAPTPTGER4CCR2PIN1POLB | |
| SCHEMBL4907245 | 0.80 | TSHR (0.51) | MAPTPTGER4CCR2PIN1POLB | |
| SCHEMBL4907252 | 0.80 | TSHR (0.51) | MAPTPTGER4CCR2PIN1POLB | |
| SCHEMBL11005079 | 0.79 | TDP1 (0.54) | CCR2PIN1PPARGMEN1KMT2A | |
| SCHEMBL4913347 | 0.79 | MAPT (0.56) | MAPTPTGER4CCR2POLBMEN1 | |
| SCHEMBL10499411 | 0.78 | MAPK1 (0.62) | MAPTPIN1PPARGMEN1KMT2A | |
| SCHEMBL306660 | 0.78 | PIN1 (0.62) | MAPTPIN1MEN1KMT2ATTR | |
| SCHEMBL9175457 | 0.77 | L3MBTL1 (0.49) | MAPTPTGER4PIN1PTGER2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | MAPT 3959/4885PTGER4 343/4885CCR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.