Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18776557 | 0.77 | S1PR1 (0.39) | TP53SMN1; SMN2KDM4EL3MBTL1KMT2A | |
| SCHEMBL1425804 | 0.70 | CYP2A6 (0.40) | PDK2LMNATP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL490759 | 0.69 | SMN1; SMN2 (0.40) | PDK2TP53SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL3789310 | 0.68 | NQO1 (0.52) | LMNATP53KDM4EL3MBTL1CYP3A4 | |
| SCHEMBL490794 | 0.67 | RELA (0.40) | LMNASMN1; SMN2KDM4EL3MBTL1KMT2A | |
| SCHEMBL14085522 | 0.67 | TP53 (0.49) | PDK2LMNATP53SMN1; SMN2KDM4E | |
| SCHEMBL490802 | 0.65 | ALDH1A1 (0.41) | PDK2TP53SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10784591 | 0.65 | SMN1; SMN2 (0.50) | LMNATP53SMN1; SMN2L3MBTL1CYP3A4 | |
| SCHEMBL11268438 | 0.65 | ALDH1A1 (0.43) | LMNAKDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3786617 | 0.65 | NQO1 (0.52) | LMNASMN1; SMN2KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803034-A2 | HOLOGRAPHIC STORAGE MEDIUM | General Electric Company (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044243-A2 | HOLOGRAPHIC STORAGE MEDIUM | GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) | 2006-04-27 | — | — | WO | disclosed |