SCHEMBL4909389

SCHEMBL4909389

C=C(C)C(=O)NCOC(C)CC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
TSHR P16473 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5856243 0.89 TSHR (0.31) TSHR
SCHEMBL855074 0.82 TGFBR1 (0.37) TGFBR1TSHRRXFP1THRBALDH1A1
SCHEMBL19821916 0.80 MTNR1A (0.37) TSHRTHRBALDH1A1
SCHEMBL14489309 0.80 TGM2 (0.31)
SCHEMBL339706 0.76 TSHR (0.38) TGFBR1TSHRRXFP1THRBALDH1A1
SCHEMBL8794243 0.74 TSHR (0.43) TSHRALDH1A1
SCHEMBL2346839 0.73 ALDH1A1 (0.40) TGFBR1TSHRRXFP1THRBALDH1A1
SCHEMBL19822018 0.73 HSD17B10 (0.31) TSHR
SCHEMBL27387827 0.73 TGFBR1 (0.36) TGFBR1TSHRRXFP1ALDH1A1
SCHEMBL8416650 0.73 TGFBR1 (0.33) TGFBR1TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080139736-A1 AQUEOUS CURABLE RESIN COMPOSITION AND AQUEOUS COATING COMPOSITION NIPPON PAINT CO., LTD (JP) 2008-06-12 US disclosed
US-7235342-B2 Negative photoresist composition including non-crosslinking chemistry INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-06-26 US disclosed
US-7235342-B2 Negative photoresist composition including non-crosslinking chemistry INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-06-26 US disclosed
EP-0407858-A1 Polymer composition having improved durability and method relating thereto THE B.F. GOODRICH COMPANY (US) 1991-01-16 EP disclosed
US-RE31985-E UNSATURATED POLYESTER, SURFACTANT AND THICKENER Dai Nippon Toryo Co, Ltd. (JP) 1985-09-17 US disclosed
EP-0067308-B1 NEUTRALIZING LAYER FOR COLOR TRANSFER ASSEMBLAGES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-03-27 EP disclosed
US-4389479-A Neutralizing layer for color transfer assemblages EASTMAN KODAK COMPANY (US) 1983-06-21 US disclosed
EP-0067308-A1 Neutralizing layer for color transfer assemblages EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP disclosed
US-4296014-A COMPRISING A POLYESTER-ACRYLIC CROSSLINKABLE GRAFT POLYMER AND A SURFACTANT OR THICKENER DAI NIPPON TORYO CO., LTD. (JP) 1981-10-20 US disclosed