Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910158 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19OGFRL1 | |
| SCHEMBL4915657 | 0.82 | OGFRL1 (0.43) | OGFRL1OPRM1OPRD1OPRK1MAPT | |
| SCHEMBL4917592 | 0.80 | HDAC3 (0.56) | OGFRL1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4919026 | 0.80 | OPRM1 (0.44) | OGFRL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4918096 | 0.78 | TSHR (0.41) | OGFRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4918061 | 0.74 | NR4A2 (0.46) | OGFRL1OPRM1OPRD1OPRK1RAB9A | |
| SCHEMBL6528422 | 0.72 | L3MBTL1 (0.60) | OGFRL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL1170660 | 0.72 | ALDH1A1 (0.86) | CYP1A2CYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL42480 | 0.72 | TP53 (0.47) | CYP2D6OGFRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL15576001 | 0.70 | GSK3B (0.47) | OGFRL1OPRM1OPRD1OPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | ICAGEN, INC. (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | TRPV3, SCN3A, TRPV1 | CYP1A2 3200/4885CYP3A4 3795/4885CYP2D6 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.