SCHEMBL491150

SCHEMBL491150

CCc1[c]c(CC)cc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15063566 0.87
SCHEMBL15067532 0.87
SCHEMBL28331835 0.85 GABRA1 (0.30)
SCHEMBL263267 0.74 NOS3 (0.34)
SCHEMBL147391 0.74 PTGS2 (0.37)
SCHEMBL28453454 0.72 PTGS2 (0.36)
SCHEMBL9487944 0.72
SCHEMBL9197765 0.72
SCHEMBL508938 0.72 TSHR (0.37)
SCHEMBL2467446 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178267-A Chiral N-heterocyclic carbene nitrile oxide adduct organic catalyst and application thereof 大连理工大学 2023-05-30 CN claimed
EP-0292990-B1 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEM (JP) 1995-02-01 EP claimed
US-4978385-A 4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1990-12-18 US claimed
US-4886546-A Pyrone-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1989-12-12 US claimed
EP-0292990-A1 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1988-11-30 EP claimed
CN-116178267-B Chiral N-heterocyclic carbene nitrile oxide adduct organic catalyst and application thereof 大连理工大学 2024-06-28 CN disclosed
CN-116178267-A Chiral N-heterocyclic carbene nitrile oxide adduct organic catalyst and application thereof 大连理工大学 2023-05-30 CN disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
CN-104277004-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-104326952-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
EP-3045450-A1 INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 2016-07-20 EP disclosed
EP-2614053-B1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2016-03-23 EP disclosed
WO-2005085253-A1 PYRROLOPYRIMIDINE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-09-15 WO disclosed
WO-2005066178-A1 TRIAZA-CYCLOPENTA[CD]INDENE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-07-21 WO disclosed
WO-2005066142-A2 PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-07-21 WO disclosed
WO-2005066182-A1 THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-07-21 WO disclosed
EP-1467997-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP Taisho Pharmaceutical Co. Ltd. (JP) 2004-10-20 EP disclosed
WO-2004058767-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-07-15 WO disclosed
US-4764624-A 1,2,5-Substituted imidazole compounds and their use as growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed
CN-87101796-A The manufacture method of 1-phenylimidazole-carboxylic acid amide and as the application of plant-growth regulator 1987-09-23 CN disclosed