SCHEMBL508938

SCHEMBL508938

CCc1[c]c(CC)cc(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27752027 0.89 PNMT (0.30)
SCHEMBL458008 0.87 TSHR (0.32) TSHR
SCHEMBL4195061 0.85 TSHR (0.30) TSHR
SCHEMBL509822 0.80 PTGS2 (0.32)
SCHEMBL509857 0.77 AHR (0.45) ALDH1A1
SCHEMBL147391 0.74 PTGS2 (0.37)
SCHEMBL263267 0.74 NOS3 (0.34) TSHRALDH1A1
SCHEMBL491150 0.72
SCHEMBL9197765 0.72
SCHEMBL2467446 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1278272-A Polymerization catalysts BP CHEM INT LTD (GB) 2000-12-27 CN claimed
EP-0292990-B1 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEM (JP) 1995-02-01 EP claimed
US-4978385-A 4-halopyridine-3-carboxamide compounds and herbicidal compositions thereof DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1990-12-18 US claimed
US-4886546-A Pyrone-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1989-12-12 US claimed
EP-0292990-A1 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1988-11-30 EP claimed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
CN-104326952-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-104277004-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
EP-3045450-A1 INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 2016-07-20 EP disclosed
EP-2614053-B1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2016-03-23 EP disclosed
CN-103180300-B Process for producing pyridazinone compound and intermediate thereof SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-10-07 CN disclosed
US-9040709-B2 Method for producing pyridazinone compounds and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-26 US disclosed
WO-2009035150-A2 4-PHENYL-5-HYDROXY-3(2H)-PYRIDAZINONE DERIVATIVES AS HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 WO disclosed
CN-100457695-C Chain extension reaction method BP CHEMCALS LTD (GB) 2009-02-04 CN disclosed
CN-101277981-A Diene polymerisation INEOS EUROPE LTD (GB) 2008-10-01 CN disclosed
CN-101263163-A Transition metal complexes supported on activating fluorinated support TOTAL PETROCHEMICALS RES FELUY (BE) 2008-09-10 CN disclosed
CN-101248094-A Activating fluorinated supports with iron-based non-metallocene complexes TOTAL PETROCHEMICALS RES FELUY (BE) 2008-08-20 CN disclosed
CN-101070261-A Chain growth reaction process BP CHEM INT LTD (GB) 2007-11-14 CN disclosed
CN-1246341-C Polymerization catalysts BP CHEM INT LTD (GB) 2006-03-22 CN disclosed
CN-1278272-A Polymerization catalysts BP CHEM INT LTD (GB) 2000-12-27 CN disclosed