Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338603 | 0.76 | CYP2D6 (0.34) | CYP2D6 | |
| SCHEMBL7562972 | 0.74 | CYP2D6 (0.41) | CYP2D6CTSK | |
| SCHEMBL7563852 | 0.72 | CYP2D6 (0.34) | CYP2D6 | |
| SCHEMBL5577164 | 0.72 | CYP2D6 (0.39) | CYP2D6CTSK | |
| SCHEMBL13377425 | 0.72 | DGAT1 (0.33) | CYP2D6CTSK | |
| SCHEMBL13981283 | 0.71 | CYP2D6 (0.38) | CYP2D6CTSK | |
| SCHEMBL4347578 | 0.68 | CYP2D6 (0.33) | CYP2D6CTSK | |
| SCHEMBL4332980 | 0.68 | CYP2D6 (0.33) | CYP2D6CTSK | |
| SCHEMBL4332983 | 0.68 | CYP2D6 (0.33) | CYP2D6CTSK | |
| SCHEMBL9001888 | 0.68 | NR1D1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105567-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2012-01-31 | — | — | US | disclosed |
| EP-1803711-B1 | Process for the preparation of multidentate aza ligands able to complex metal ions | BRACCO IMAGING SPA (IT) | 2011-10-19 | — | — | EP | disclosed |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-04-07 | — | — | US | disclosed |
| US-7893223-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2011-02-22 | — | — | US | disclosed |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | BRACCO IMAGING S.P.A (IT) | 2010-03-18 | — | — | US | disclosed |
| EP-1803711-A1 | Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.p.A. (IT) | 2007-07-04 | — | — | EP | disclosed |
| EP-1417183-B1 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING SPA (IT) | 2007-05-23 | — | — | EP | disclosed |
| US-7186400-B2 | Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2007-03-06 | — | — | US | disclosed |
| US-20060034773-A1 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2006-02-16 | — | — | US | disclosed |
| US-20040156786-A1 | Multidentate aza ligands able to complex metal ions and the use therof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060034773-A1 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | SSTR3, MB, CA13 | CYP2D6 1494/4885CTSK 2358/4885 |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | CD99, CD209, PRMT9 | CYP2D6 1550/4885CTSK 2509/4885 |
| US-20040156786-A1 | Multidentate aza ligands able to complex metal ions and the use therof in diagnostics and therapy | SSTR1, SSTR3, TFRC | CYP2D6 2217/4885CTSK 2701/4885 |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | CD99, MB, HBZ | CYP2D6 1685/4885CTSK 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.