Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13774593 | 0.82 | RORC (0.39) | TLR7RORCTDP1 | |
| SCHEMBL4154435 | 0.81 | RORC (0.36) | TLR7RORCGPBAR1LMNATSHR | |
| SCHEMBL4144866 | 0.81 | EPAS1 (0.39) | TLR7RORCGPBAR1ALDH1A1TDP1 | |
| SCHEMBL13774589 | 0.81 | RORC (0.39) | RORCGPBAR1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4153993 | 0.80 | RORC (0.37) | TLR7RORCGPBAR1TDP1 | |
| SCHEMBL4158854 | 0.80 | RORC (0.35) | TLR7RORCGPBAR1TDP1 | |
| SCHEMBL4145216 | 0.80 | RORC (0.38) | GAARORCALDH1A1TDP1 | |
| SCHEMBL4915675 | 0.79 | TLR7 (0.38) | TLR7RORCSMN1; SMN2LMNATDP1 | |
| SCHEMBL4163087 | 0.79 | RORC (0.35) | TLR7RORCGPBAR1TDP1 | |
| SCHEMBL4908707 | 0.79 | IL2 (0.44) | TLR7GAARORCGPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | RNGTT, L3MBTL4, MYB | TLR7 1460/4885GAA 4000/4885RORC 4748/4885 |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | L3MBTL4, L3MBTL3, L3MBTL1 | TLR7 1638/4885GAA 3960/4885RORC 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.