Acetic Acid

Acetic Acid

SCHEMBL49139

CC(=O)[O-].[Hg+]c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA1 P00915 2/20 0.44
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
NAPRT Q6XQN6 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALPL P05186 1/20 0.42
POLB P06746 1/20 0.42
ALPG P10696 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX5 P09917 1/20 0.39
AKR1C3 P42330 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL12613566 0.97 CA2 (0.44) CA2CA4CA1CES2CES1
Acetic Acid SCHEMBL9450967 0.95 CA2 (0.42) CA2CA4CA1CES2CES1
Acetic Acid SCHEMBL4148336 0.91 ALDH1A1 (0.46) CA2CA4CA1CES2CES1
Acetic Acid SCHEMBL1468336 0.89 ALDH1A1 (0.44) CA2CA4CA1CES2CES1
Acetic Acid SCHEMBL14977040 0.89 OPRM1 (0.39) CA2CA4CA1CES2CES1
Bicarbonate SCHEMBL2810754 0.88 CA2 (0.50) CA2CA4CA1CES2CES1
Methacrylic Acid SCHEMBL10896945 0.85 ALDH1A1 (0.47) CA2CA4CES2CES1NAPRT
Acetic Acid SCHEMBL2811857 0.85 ALPL (0.38) CA2CA4CA1CES2CES1
Isobutyramide SCHEMBL14977038 0.85 ALOX5 (0.39) CA2CA4HSD17B10ALPLPOLB
Propionic Acid SCHEMBL448138 0.82 CES2 (0.50) CA2CA4CES2CES1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21321 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747215-A1 PYRAZOLE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR Sabic Agri-Nutrients Company (SA) 2026-05-27 EP claimed
CN-122079686-A Surfactant-assisted multi-element inorganic nano mineral modified lignin-based coating material, preparation method thereof and coated fertilizer 2026-05-26 CN claimed
CN-120310033-B PU-FC runway material with high mechanical strength and preparation method thereof 广东盛天体育股份有限公司 2026-05-19 CN claimed
WO-2026099762-A1 AMINODITHIOCARBAMATE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR SABIC Agri-Nutrients Company (SA) 2026-05-15 WO claimed
WO-2026090627-A1 STABLE PITOLISANT LIQUID FORMULATIONS AND METHOD OF ITS USE PATEL SANDIPKUMAR (US) 2026-04-30 WO claimed
EP-4731180-A1 A POWDER COMPOSITION FOR ORAL SUSPENSION OF PROTON PUMP INHIBITORS AND THE METHOD OF PREPARING THE SAME Orbit Pharma Limited (GB) 2026-04-29 EP claimed
EP-4724038-A1 PRESERVATIVE-FREE COMPOSITIONS COMPRISING A COMPLEX OF A CORTICOSTEROID AND HPBCD FOR THE TREATMENT OR PREVENTION OF AN INFLAMMATORY DISEASE THROUGH NASAL ADMINISTRATION Aquilon Pharmaceuticals (BE) 2026-04-15 EP claimed
US-20260069570-A1 STABLE PHARMACEUTICAL COMPOSITIONS OF EDARAVONE SLAYBACK PHARMA LLC (US) 2026-03-12 US claimed
WO-2025262156-A1 HYDROPHOBIC PHASE COMPOSITION COMPRISING DEHYDRATED LIPOSOMES WITH NUTRITIONAL SUPPLEMENT MIDRA B.V. (NL) 2025-12-26 WO claimed
EP-4663192-A1 PHARMACEUTICAL COMPOSITION FOR LOCAL ADMINISTRATION, PREPARATION METHOD THEREFOR, AND USE THEREOF Reistone Biopharma Company Limited (CN) 2025-12-17 EP claimed
US-4379847-A Suspending medium for immunologic reactions AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1983-04-12 US claimed
US-4329254-A CHROMATOGRAPHY CHMIELOWIEC JAN 1982-05-11 US claimed
US-4259207-A LOW IONIC STRENGTH AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1981-03-31 US claimed
US-4235236-A Device for dispensing drug by combined diffusional and osmotic operations ALZA CORPORATION (US) 1980-11-25 US claimed
US-4226854-A SURGERY, HYDROLYSIS, BROMELIN Klein, Gerold K. V. (US) 1980-10-07 US claimed
US-4197291-A BROMELING FOR DEBRIDEMENT OF TISSUES Klein, Gerold K. V. (US) 1980-04-08 US claimed
US-4188373-A Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes COOPER LABORATORIES, INC. (US) 1980-02-12 US claimed
US-4130434-A A DIIODOMETHYL SULFONE AND A PHENYLMERCURY ACYLATE ABBOTT LABORATORIES (US) 1978-12-19 US claimed
US-4085209-A PLANT FUNGICIDES ROHM AND HAAS COMPANY (US) 1978-04-18 US claimed
US-3952040-A Urea derivative containing isocyanate groups VEBA-CHEMIE AG (DT) 1976-04-20 US claimed