Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 13/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 12/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924224 | 0.94 | PLA2G10 (0.49) | PLA2G10PLA2G2APLA2G5PTGESELANE | |
| SCHEMBL4912640 | 0.88 | PTGES (0.53) | PLA2G10PLA2G2APLA2G5PTGES | |
| SCHEMBL3009731 | 0.84 | PTGES (0.52) | PTGESPOLB | |
| SCHEMBL4917266 | 0.83 | PTGES (0.44) | PTGESPOLB | |
| SCHEMBL4926174 | 0.82 | PLA2G10 (0.52) | PLA2G10PLA2G2APLA2G5PTGES | |
| SCHEMBL4922786 | 0.81 | PTGES (0.62) | PTGESPOLB | |
| SCHEMBL5265086 | 0.80 | NOD2 (0.49) | PLA2G10PTGES | |
| SCHEMBL4920933 | 0.80 | PTGES (0.48) | PTGESPOLB | |
| SCHEMBL4926021 | 0.80 | PTGES (0.61) | PLA2G10PLA2G2APLA2G5PTGESPOLB | |
| SCHEMBL4917256 | 0.80 | L3MBTL1 (0.41) | PLA2G10PLA2G2APLA2G5PTGESL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | PLA2G10 2406/4885PLA2G2A 2684/4885PLA2G5 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.