Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922695 | 0.88 | PTGES (0.48) | L3MBTL1PPARGPTGESPLA2G10PLA2G2A | |
| SCHEMBL4924224 | 0.81 | PLA2G10 (0.49) | PPARGPTGESPLA2G10PLA2G2APLA2G5 | |
| SCHEMBL4917239 | 0.80 | PLA2G10 (0.45) | L3MBTL1PTGESPLA2G10PLA2G2APLA2G5 | |
| SCHEMBL4917266 | 0.80 | PTGES (0.44) | PPARGPTGESMAPK1NOD2NOD1 | |
| SCHEMBL5265086 | 0.80 | NOD2 (0.49) | PTGESPLA2G10NOD2NOD1TP53 | |
| SCHEMBL4920933 | 0.79 | PTGES (0.48) | PTGESTP53MAPTTHRB | |
| SCHEMBL4224238 | 0.79 | PTGES (0.45) | PTGESMAPK1NOD2NOD1TP53 | |
| SCHEMBL4920937 | 0.78 | L3MBTL1 (0.50) | L3MBTL1PPARGPTGESPLA2G10PLA2G2A | |
| SCHEMBL4090093 | 0.76 | MAPT (0.41) | PPARGPTGESMAPK1P2RX3TP53 | |
| SCHEMBL4097225 | 0.75 | KDM4E (0.47) | L3MBTL1PPARGPTGESMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | L3MBTL1 2514/4885PPARG 2586/4885PTGES 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.