Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542401 | 0.84 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL4160550 | 0.83 | PTGS2 (0.41) | PTGS2PTGS1SLC6A3SLC6A2 | |
| SCHEMBL6569016 | 0.74 | CYP2A6 (0.33) | PTGS2PTGS1 | |
| SCHEMBL4924013 | 0.74 | ALDH1A1 (0.41) | PTGS2PTGS1 | |
| SCHEMBL5696523 | 0.74 | TRPV4 (0.39) | PTGS2PTGS1 | |
| SCHEMBL17287535 | 0.74 | CA1 (0.52) | PTGS2PTGS1 | |
| SCHEMBL2941459 | 0.71 | CA2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL12923865 | 0.71 | — | — | |
| SCHEMBL17685396 | 0.71 | — | — | |
| SCHEMBL6068893 | 0.70 | HDAC4 (0.42) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188088-B2 | Ethenyl carboxamide derivatives useful as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-29 | — | — | US | disclosed |
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| WO-2007144174-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CD14, MSR1, ELANE | PTGS2 938/4885PTGS1 747/4885SLC6A3 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.