Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493557 | 0.94 | ALDH1A1 (0.41) | EPHX2GAAALDH1A1PKMPOLB | |
| SCHEMBL492672 | 0.90 | EPHX2 (0.39) | EPHX2GAAALDH1A1PKMPOLB | |
| SCHEMBL492562 | 0.90 | EPHX2 (0.41) | EPHX2GAAEBPDHCR7ALDH1A1 | |
| SCHEMBL493115 | 0.89 | ALDH1A1 (0.43) | EPHX2GAAALDH1A1PKM | |
| SCHEMBL493337 | 0.88 | EPHX2 (0.40) | EPHX2GAAALDH1A1PKM | |
| SCHEMBL492906 | 0.88 | EPHX2 (0.47) | EPHX2EBPDHCR7 | |
| SCHEMBL492783 | 0.88 | ALDH1A1 (0.43) | EPHX2ALDH1A1PKMPOLBATM | |
| SCHEMBL492701 | 0.86 | EPHX2 (0.36) | EPHX2GAAALDH1A1PKMPOLB | |
| SCHEMBL492692 | 0.86 | PKM (0.43) | EPHX2ALDH1A1PKMPOLB | |
| SCHEMBL493083 | 0.85 | EPHX2 (0.41) | EPHX2GAAALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | EPHX2 2567/4885GAA 445/4885EBP 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.