Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.32 |
| ▸ | GLRB | P48167 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10813783 | 0.83 | TSHR (0.54) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL4924130 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL12406472 | 0.81 | L3MBTL1 (0.40) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL4923849 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL15097114 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL2182723 | 0.79 | ALDH1A1 (0.37) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL4915349 | 0.78 | HTT (0.47) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL397236 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL28308139 | 0.77 | TSHR (0.49) | SMN1; SMN2L3MBTL1MEN1GALR3HTT | |
| SCHEMBL28127457 | 0.76 | TSHR (0.41) | SMN1; SMN2L3MBTL1MEN1GALR3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | MEN TEWA | 2008-09-18 | — | — | US | claimed |
| EP-1232748-B1 | USE OF SUBSTITUTED NITROBENZENE DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY BACTERIA, FUNGI AND VIRUSES | MEN TEWA (CN) | 2006-05-03 | — | — | EP | claimed |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | MEN TEWA | 2005-10-13 | — | — | US | claimed |
| EP-1232748-A1 | SUBSTITUTED NITROBENZENE DERIVATIVES AS MEDICINES AND OTHER USEFUL USES THEREOF | Men, Tewa (CN) | 2002-08-21 | — | — | EP | claimed |
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | MEN TEWA | 2008-09-18 | — | — | US | disclosed |
| EP-1232748-B1 | USE OF SUBSTITUTED NITROBENZENE DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY BACTERIA, FUNGI AND VIRUSES | MEN TEWA (CN) | 2006-05-03 | — | — | EP | disclosed |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | MEN TEWA | 2005-10-13 | — | — | US | disclosed |
| EP-1232748-A1 | SUBSTITUTED NITROBENZENE DERIVATIVES AS MEDICINES AND OTHER USEFUL USES THEREOF | Men, Tewa (CN) | 2002-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227869-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses thereof | NOS3, NOS1, PTGS1 | SMN1; SMN2 939/4885L3MBTL1 3017/4885MEN1 2911/4885 |
| US-20050228055-A1 | Substituted nitrobenzene derivatives as pharmaceutical and other uses athereof | APOB, NDUFB1, CYP2F1 | SMN1; SMN2 2174/4885L3MBTL1 4545/4885MEN1 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.