SCHEMBL492596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL492975	0.99	CACNA2D1 (0.37)	ALDH1A1TDP1CACNA2D1CACNA1BCACNB1
	SCHEMBL493117	0.93	CACNA2D1 (0.42)	CACNA2D1CACNA1BCACNB1CACNA1CBDKRB1
	SCHEMBL492867	0.93	BDKRB1 (0.39)	ALDH1A1TDP1CACNA2D1CACNA1BCACNB1
	SCHEMBL493013	0.93	MEN1 (0.37)	CACNA2D1CACNA1BCACNB1CACNA1CBDKRB1
	SCHEMBL493360	0.91	LMNA (0.39)	ALDH1A1TDP1BDKRB1SMN1; SMN2LMNA
	SCHEMBL492976	0.91	ALDH1A1 (0.37)	ALDH1A1TDP1CACNA2D1CACNA1BCACNB1
	SCHEMBL493689	0.90	CACNA2D1 (0.37)	ALDH1A1TDP1CACNA2D1CACNA1BCACNB1
	SCHEMBL493184	0.90	POLB (0.36)	ALDH1A1TDP1CACNA2D1CACNA1BCACNB1
	SCHEMBL493688	0.89	PTGIR (0.37)	CACNA2D1CACNA1BCACNB1CACNA1CBDKRB1
	SCHEMBL644329	0.88	CACNA2D1 (0.37)	ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.