SCHEMBL4929484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4928495	0.94	PTGDR2 (0.50)	PTGDR2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4932239	0.91	IDH1 (0.42)	PTGDR2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL4925811	0.85	METAP2 (0.45)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL4930768	0.80	ALDH1A1 (0.53)	HDAC6IDH1SMN1; SMN2NPC1POLB
	SCHEMBL4930035	0.79	ALDH1A1 (0.50)	SMN1; SMN2NPC1RAB9ATP53MAPK1
	SCHEMBL4926357	0.73	DRD2 (0.55)	PTGDR2DRD2TBXA2RSMN1; SMN2TP53
	SCHEMBL4930112	0.73	TP53 (0.52)	DRD2TBXA2RSMN1; SMN2NPC1TP53
	SCHEMBL14463849	0.73	TP53 (0.52)	NPC1TP53MAPK1POLBMAPT
	SCHEMBL28462923	0.72	DRD2 (0.62)	PTGDR2DRD2TBXA2RSMN1; SMN2NPC1
	SCHEMBL28461433	0.72	MAPT (0.59)	PTGDR2DRD2TBXA2RSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.