Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239973 | 0.88 | HRH3 (0.44) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL27751855 | 0.87 | HTR2A (0.41) | SLC6A2SLC6A4SLC6A3HTR2ACYP2A6 | |
| SCHEMBL20896988 | 0.80 | OPRM1 (0.44) | HRH3OPRM1OPRD1OPRK1 | |
| SCHEMBL1005726 | 0.79 | G6PC1 (0.47) | SMN1; SMN2TAAR1HRH3 | |
| SCHEMBL25992610 | 0.77 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3HTR2ACYP2A6 | |
| Benzylamine SCHEMBL28194825 | 0.74 | LOXL2 (0.64) | SLC6A2SLC6A4SLC6A3HTR2ACYP2A6 | |
| SCHEMBL5525779 | 0.72 | GBA1 (0.59) | CCR3 | |
| SCHEMBL5525774 | 0.72 | GBA1 (0.59) | CCR3 | |
| Ethylbenzene SCHEMBL29268284 | 0.71 | TP53 (0.58) | SLC6A2SLC6A4SLC6A3HTR2ACYP2A6 | |
| SCHEMBL5513756 | 0.70 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | SLC6A2 2372/4885SLC6A4 2704/4885SLC6A3 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.