Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.38 |
| ▸ | PTGIR | P43119 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494153 | 0.95 | PTGIR (0.35) | BDKRB1PTGIRHTR6OPRL1TACR3 | |
| SCHEMBL492894 | 0.92 | BDKRB1 (0.37) | BDKRB1HTR6OPRL1TACR3NR1H4 | |
| SCHEMBL493135 | 0.92 | BDKRB1 (0.39) | BDKRB1PTGIRHTR6NR1H4GRM5 | |
| SCHEMBL493901 | 0.91 | PTGIR (0.41) | BDKRB1PTGIR | |
| SCHEMBL493579 | 0.90 | CXCR3 (0.38) | PTGIRHTR6OPRL1SLC9A3 | |
| SCHEMBL492558 | 0.90 | HTR7 (0.35) | BDKRB1PTGIRHTR6OPRL1OPRM1 | |
| SCHEMBL492545 | 0.89 | BDKRB1 (0.39) | BDKRB1OPRL1TACR3 | |
| SCHEMBL493251 | 0.89 | HTR6 (0.38) | PTGIRHTR6OPRL1 | |
| SCHEMBL493380 | 0.89 | BDKRB1 (0.40) | BDKRB1PTGIRSLC9A3 | |
| SCHEMBL492577 | 0.88 | SLC9A3 (0.36) | BDKRB1PTGIROPRL1TACR3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | BDKRB1 1622/4885PTGIR 121/4885HTR6 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.