Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117768 | 0.87 | BDKRB1 (0.57) | ALDH1A1L3MBTL1BDKRB1PTGDR2GSTO1 | |
| SCHEMBL5114284 | 0.85 | HTT (0.48) | ALDH1A1L3MBTL1BDKRB1GSTO1 | |
| SCHEMBL493566 | 0.83 | BDKRB1 (0.42) | ALDH1A1L3MBTL1BDKRB1PTGDR2TDP1 | |
| SCHEMBL14033580 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1BDKRB1PTGDR2TDP1 | |
| SCHEMBL493230 | 0.82 | PTGDR2 (0.49) | ALDH1A1PTGDR2TDP1TSHRPOLB | |
| SCHEMBL4464906 | 0.81 | BDKRB1 (0.56) | ALDH1A1L3MBTL1BDKRB1PTGDR2TDP1 | |
| SCHEMBL14034060 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1BDKRB1TRPV4GSTO1 | |
| SCHEMBL5125397 | 0.80 | BDKRB1 (0.55) | ALDH1A1L3MBTL1BDKRB1PTGDR2GSTO1 | |
| SCHEMBL14034027 | 0.80 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1BDKRB1PTGDR2TDP1 | |
| SCHEMBL3442606 | 0.79 | BDKRB1 (0.44) | ALDH1A1L3MBTL1BDKRB1PTGDR2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | ALDH1A1 1349/4885L3MBTL1 4753/4885BDKRB1 1622/4885 |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | ALDH1A1 863/4885L3MBTL1 4883/4885BDKRB1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.