Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.42 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162928 | 0.87 | ALDH1A1 (0.38) | MGLLPTGS2LMNA | |
| SCHEMBL4927321 | 0.86 | MGLL (0.56) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL4931612 | 0.83 | MARS1 (0.51) | MEN1KMT2A | |
| SCHEMBL4929746 | 0.83 | MGLL (0.51) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL4933534 | 0.82 | NFE2L2 (0.41) | MGLLPTGS2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2919194 | 0.81 | PTGS2 (0.49) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL2912233 | 0.80 | PTGS2 (0.51) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL4927988 | 0.80 | MGLL (0.49) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL4932636 | 0.79 | MGLL (0.53) | MGLLPTGS2MEN1MAPTKMT2A | |
| SCHEMBL5529669 | 0.78 | CNR1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | MGLL 4785/4885PTGS2 2158/4885MEN1 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.