Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 15/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711584 | 0.89 | HDAC1 (0.47) | HDAC1HDAC6CXCR4ADRA2AADRA1D | |
| SCHEMBL5057520 | 0.89 | HDAC1 (0.46) | HDAC1HDAC6CXCR4ADRA2ASLC40A1 | |
| SCHEMBL30379489 | 0.82 | HDAC1 (0.61) | HDAC1HDAC6CXCR4SLC40A1CYP2D6 | |
| SCHEMBL13909820 | 0.82 | HDAC1 (0.76) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL6047459 | 0.81 | HDAC1 (0.41) | HDAC1HDAC6CXCR4SLC40A1CHRM2 | |
| SCHEMBL4887341 | 0.80 | HDAC1 (0.69) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL4562865 | 0.80 | HDAC1 (0.69) | HDAC1HDAC6CXCR4CYP2D6 | |
| SCHEMBL31257251 | 0.80 | SLC40A1 (0.59) | CXCR4SLC40A1CHRM2CYP2D6DRD2 | |
| SCHEMBL4760828 | 0.80 | SLC40A1 (0.59) | CXCR4SLC40A1CHRM2CYP2D6DRD2 | |
| SCHEMBL3370850 | 0.80 | SLC40A1 (0.59) | CXCR4SLC40A1CHRM2CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096861-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096861-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | HDAC1 844/4885HDAC6 568/4885CXCR4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.