SCHEMBL493369

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL493372	0.89	MAPT (0.39)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL493370	0.86	KMT2A (0.45)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL432792	0.84	KMT2A (0.52)	KMT2ALMNAMAPTNPSR1HTT
	Chloroacetic Acid SCHEMBL494452	0.78	LMNA (0.44)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL432793	0.75	LMNA (0.45)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL21952688	0.75	KMT2A (0.42)	KMT2ALMNAMAPTNPSR1HPGD
	SCHEMBL5542753	0.72	KMT2A (0.53)	KMT2ALMNAMAPTHTTHPGD
	SCHEMBL11430439	0.72	KMT2A (0.52)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL493850	0.71	MAPT (0.45)	KMT2ALMNAMAPTNPSR1HTT
	SCHEMBL494453	0.70	LMNA (0.44)	KMT2ALMNAMAPTNPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.