Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 2/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.46 |
| ▸ | CBX7 | O95931 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741979 | 0.94 | FADS1 (0.48) | AURKAAURKBFADS1SMN1; SMN2MEN1 | |
| SCHEMBL4740979 | 0.87 | FADS1 (0.50) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4740978 | 0.87 | FADS1 (0.49) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4937692 | 0.86 | FADS1 (0.46) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4741010 | 0.86 | FADS1 (0.48) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4740936 | 0.83 | FADS1 (0.49) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4741728 | 0.82 | FADS1 (0.55) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4785627 | 0.81 | KDR (0.54) | AURKAAURKBFADS1SMN1; SMN2MEN1 | |
| SCHEMBL4739356 | 0.81 | FADS1 (0.51) | FADS1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4785097 | 0.80 | FADS1 (0.53) | FADS1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216316-A1 | DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC | BUCK INST RES AGING (US) | 2024-07-04 | — | — | US | disclosed |
| US-20080200458-A1 | Methods and compositions for the treatment of body composition disorders | LEXICON PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | disclosed |
| US-20080194557-A1 | Methods and compositions for the treatment of pain, inflammation and cancer | LEXICON PHARMACEUTICALS, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194557-A1 | Methods and compositions for the treatment of pain, inflammation and cancer | TNF, IL6, CXCL8 | AURKA 2862/4885AURKB 2767/4885FADS1 1059/4885 |
| US-20240216316-A1 | DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC | DAGLA, DAGLB, MGLL | AURKA 4214/4885AURKB 2913/4885FADS1 192/4885 |
| US-20080200458-A1 | Methods and compositions for the treatment of body composition disorders | CPT1B, CPT1A, SHBG | AURKA 4786/4885AURKB 4557/4885FADS1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.