Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493514 | 0.85 | HDAC4 (0.44) | KMT2ANPC1MEN1MAPTLMNA | |
| SCHEMBL494415 | 0.83 | TSHR (0.42) | KMT2APOLBNPC1ALDH1A1TSHR | |
| SCHEMBL493621 | 0.81 | CYP2D6 (0.45) | NPC1ALDH1A1SMN1; SMN2TACR3 | |
| SCHEMBL1327843 | 0.79 | LMNA (0.45) | NPC1LMNASMN1; SMN2MTTP | |
| SCHEMBL493256 | 0.79 | SMN1; SMN2 (0.44) | KMT2APOLBNPC1MEN1MAPT | |
| SCHEMBL1328275 | 0.79 | DRD2 (0.42) | POLBHCRTR1HCRTR2 | |
| SCHEMBL492929 | 0.77 | RAB9A (0.37) | TSHRSLC6A9LMNATP53 | |
| SCHEMBL492704 | 0.74 | OPRL1 (0.44) | — | |
| SCHEMBL493393 | 0.74 | OPRL1 (0.44) | — | |
| SCHEMBL493737 | 0.74 | KMT2A (0.49) | KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |