Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493737 | 0.89 | KMT2A (0.49) | KMT2AHPGDPOLB | |
| SCHEMBL492929 | 0.88 | RAB9A (0.37) | TSHRRAB9ATP53HPGD | |
| SCHEMBL493502 | 0.86 | KMT2A (0.40) | TSHRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL493600 | 0.85 | GHSR (0.40) | KMT2ANPC1RAB9APKMPOLB | |
| SCHEMBL493820 | 0.85 | RAB9A (0.40) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL493863 | 0.84 | LMNA (0.48) | KMT2ASMN1; SMN2PKM | |
| SCHEMBL493779 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL492913 | 0.84 | RAB9A (0.39) | ALDH1A1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL493647 | 0.83 | KDM4E (0.48) | ALDH1A1KMT2ANPC1TP53HTT | |
| SCHEMBL493708 | 0.83 | KMT2A (0.39) | TSHRALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |