Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 4/20 | 0.45 |
| ▸ | EDNRA | P25101 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
| ▸ | ME3 | Q16798 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764429 | 0.79 | EDNRB (0.59) | PABPC1EIF4HEDNRBEDNRAALDH1A1 | |
| SCHEMBL5889114 | 0.74 | TUBB4A (0.59) | PABPC1EIF4HEDNRBEDNRAALDH1A1 | |
| SCHEMBL4938247 | 0.67 | TUBB4A (0.43) | MPOCYSLTR1KMT2ATUBB4ATUBB | |
| SCHEMBL15659459 | 0.66 | MPO (0.61) | EDNRAME2ME1ME3MPO | |
| SCHEMBL9536999 | 0.66 | KDM4E (0.43) | PABPC1EIF4HEDNRBEDNRAALDH1A1 | |
| SCHEMBL5744199 | 0.63 | MPO (0.57) | EDNRAAPPME2ME1ME3 | |
| SCHEMBL6817003 | 0.62 | EDNRA (0.41) | EDNRBEDNRAMPOCYSLTR1ALDH1A1 | |
| SCHEMBL9537134 | 0.61 | KDM4E (0.58) | PABPC1EIF4HEDNRBEDNRAALDH1A1 | |
| SCHEMBL21465511 | 0.60 | MEN1 (0.67) | PABPC1EIF4HEDNRBEDNRAALDH1A1 | |
| SCHEMBL4762798 | 0.60 | TUBB4A (0.74) | MEN1KMT2ATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287469-A1 | Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation | DIACOVO THOMAS G | 2008-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287469-A1 | Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation | PI4KB, PIK3CA, PI4KA | PABPC1 2102/4885EIF4H 3434/4885EDNRB 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.