Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.70 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.68 |
| ▸ | TDP2 | O95551 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | NMT1 | P30419 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955720 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL4937842 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL20998498 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL11502177 | 0.94 | CASP3 (0.67) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL2831352 | 0.92 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL1169889 | 0.92 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL1683255 | 0.92 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL9360711 | 0.90 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL29262225 | 0.90 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4ELPAR2LPAR3 | |
| SCHEMBL15667293 | 0.90 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4ELPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342126-B2 | Process for the preparation of 4-oxo-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION (US) | 2008-03-11 | — | — | US | claimed |
| WO-2006049676-A1 | PROCESS FOR THE PREPARATION OF 4-OXO-4-((4-(PHENYLAMINO) AMINO)-2-BUTENOIC ACID | CHEMTURA CORPORATION (US) | 2006-05-11 | — | — | WO | claimed |
| US-20060089511-A1 | Process for the preparation of 4-OXO-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION | 2006-04-27 | — | — | US | claimed |
| US-5936038-A | MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE | THE UNIVERSITY OF AKRON (US) | 1999-08-10 | — | — | US | claimed |
| CN-117916283-A | Curable conductive composition | 贺利氏电子化学材料有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-7342126-B2 | Process for the preparation of 4-oxo-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342126-B2 | Process for the preparation of 4-oxo-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342126-B2 | Process for the preparation of 4-oxo-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| WO-2006049676-A1 | PROCESS FOR THE PREPARATION OF 4-OXO-4-((4-(PHENYLAMINO) AMINO)-2-BUTENOIC ACID | CHEMTURA CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |
| WO-2006049676-A1 | PROCESS FOR THE PREPARATION OF 4-OXO-4-((4-(PHENYLAMINO) AMINO)-2-BUTENOIC ACID | CHEMTURA CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20060089511-A1 | Process for the preparation of 4-OXO-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION | 2006-04-27 | — | — | US | disclosed |
| US-20060089511-A1 | Process for the preparation of 4-OXO-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | CROMPTON CORPORATION | 2006-04-27 | — | — | US | disclosed |
| EP-0029598-A1 | An improved high solids coating composition of a low molecular weight acrylic polymer and a polyisocyanate cross-linking agent, and a substrate coated therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029595-A1 | An improved high solids coating composition of a low molecular weight glycidyl acrylic polymer and an alkylated melamine cross-linking agent, and a substrate coated therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029596-A1 | An improved high solids coating composition of a low molecular weight acrylic polymer and a nitrogen resin cross-linking agent, and a substrate coated therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029594-A1 | A liquid acrylic coating composition, articles coated therewith and process for preparing said coated articles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029597-A1 | An aqueous thermosetting acrylic coating composition, articles coated therewith, and process for preparing said coated articles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029593-A1 | A coating composition based on acrylic polymer blends, articles coated therewith, and process for preparing said coated articles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| WO-1981000233-A1 | CLEAR COAT/COLOR COAT FINISH CONTAINING AN ULTRAVIOLET LIGHT STABILIZER | DU PONT | 1981-02-05 | — | — | WO | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089511-A1 | Process for the preparation of 4-OXO-4-((4-(phenylamino)phenyl)amino)-2-butenoic acid | ALOX5, ALAD, ALOX15 | ALDH1A1 1139/4885MAPT 2401/4885KDM4E 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.