Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736647 | 0.98 | HRH3 (0.41) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL737728 | 0.97 | HRH3 (0.41) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL737369 | 0.96 | HRH3 (0.42) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL737545 | 0.80 | MAPT (0.50) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL4536337 | 0.79 | OPRM1 (0.52) | CHRM4MEN1KMT2A | |
| SCHEMBL737726 | 0.75 | MAPT (0.48) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL737638 | 0.74 | RAB9A (0.46) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL735913 | 0.72 | KDM4E (0.48) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL4940044 | 0.72 | KDM4E (0.51) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL945189 | 0.72 | ME2 (0.60) | MAPTALDH1A1LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228127-B | Piperidine derivatives | BANYU PHARMA CO LTD | 2012-05-16 | — | — | CN | disclosed |
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |