SCHEMBL4942839

SCHEMBL4942839

C=CCN(CC=C)Cc1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
HSPA5 P11021 1/20 0.46
APAF1 O14727 1/20 0.44
NSD2 O96028 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
HIF1A Q16665 1/20 0.42
HTR1A P08908 2/20 0.42
OPRK1 P41145 3/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR1D P28221 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR1E P28566 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11667015 0.85 ALDH1A1 (0.56) ALDH1A1LMNAHTTAPAF1NSD2
SCHEMBL11304680 0.83 HTR1A (0.59) ALDH1A1LMNAHTTHSPA5HTR1A
SCHEMBL15283002 0.83 HSPA5 (0.59) ALDH1A1LMNAHSPA5CYP2D6TSHR
SCHEMBL18868170 0.82 ALDH1A1 (0.42) ALDH1A1LMNAHTTHTR1AOPRK1
SCHEMBL9418484 0.82 GABRA1 (0.47) ALDH1A1LMNAHTTAPAF1NSD2
SCHEMBL5820317 0.80 APAF1 (0.51) ALDH1A1LMNAHTTAPAF1NSD2
SCHEMBL9395374 0.79 HSPA5 (0.54) HSPA5CYP2D6TSHRHIF1AHTR1A
SCHEMBL9418481 0.77 XDH (0.44) ALDH1A1LMNAHTTAPAF1NSD2
SCHEMBL5823545 0.77 ALDH1A1 (0.56) ALDH1A1LMNAHTTAPAF1NSD2
SCHEMBL1110914 0.76 ALDH1A1 (0.49) ALDH1A1LMNAHTTAPAF1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076885-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US claimed
WO-2008036454-A1 POLY (ARYLENE ETHER) COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-03-27 WO claimed
EP-0469811-B1 Accelerators for curing phenolic resole resins BORDEN INC (US) 1994-11-30 EP claimed
EP-0469811-A2 Accelerators for curing phenolic resole resins Borden, Inc. (US) 1992-02-05 EP claimed
EP-0107101-B1 CATHODIC ELECTRODEPOSITION OF CHARGED AQUEOUS POWDER SLURRY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-30 EP claimed
EP-0106355-B1 ANODIC ELECTRODEPOSITION OF CHARGED AQUEOUS POWDER SLURRY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-15 EP claimed
US-3935160-A OXIDATION RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US claimed
JP-55056173-A None JP disclosed
EP-2917181-B1 HETEROARYL DERIVATIVES AND USES THEREOF JACOBUS PHARMACEUTICAL COMPANY INC (US) 2019-09-25 EP disclosed
US-9409893-B2 Heteroaryl derivatives and uses thereof JACOBUS PHARMACEUTICAL COMPANY, INC. (US) 2016-08-09 US disclosed
US-9296696-B2 Aryl derivatives and uses thereof JACOBUS PHARMACEUTICALS COMPANY, INC. (US) 2016-03-29 US disclosed
EP-2917181-A1 HETEROARYL DERIVATIVES AND USES THEREOF Jacobus Pharmaceutical Company, Inc. (US) 2015-09-16 EP disclosed
EP-2917200-A1 ARYL DERIVATIVES AND USES THEREOF Jacobus Pharmaceutical Company, Inc. (US) 2015-09-16 EP disclosed
US-4091037-A FROM DIALKYLAMINOMETHYLPHENOL AND THIOCARBOXYLIC ACID S-ESTER BAYER AKTIENGESELLSCHAFT (DT) 1978-05-23 US disclosed
US-4091037-A FROM DIALKYLAMINOMETHYLPHENOL AND THIOCARBOXYLIC ACID S-ESTER BAYER AKTIENGESELLSCHAFT (DT) 1978-05-23 US disclosed
US-4014955-A Process for the manufacture of polyethers containing ionic bonds CIBA-GEIGY AG (CH) 1977-03-29 US disclosed
US-4000116-A BISTERT-AMINOMETHYL POLYHYDRIC PHENOLS, HALOGENATED EPOXIDES CIBA-GEIGY CORPORATION (US) 1976-12-28 US disclosed
US-3935160-A OXIDATION RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US disclosed
US-3935160-A OXIDATION RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US disclosed
US-3935160-A OXIDATION RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US disclosed