Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667015 | 0.82 | ALDH1A1 (0.56) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL4942839 | 0.82 | ALDH1A1 (0.53) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL5820317 | 0.78 | APAF1 (0.51) | GABRA1GABRB2OPRM1OPRD1OPRK1 | |
| SCHEMBL9418482 | 0.78 | OPRM1 (0.41) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL18868170 | 0.77 | ALDH1A1 (0.42) | GABRA1GABRB2OPRM1OPRD1OPRK1 | |
| SCHEMBL9286785 | 0.76 | AMY1A (0.39) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL11266199 | 0.74 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1LMNAHTT | |
| SCHEMBL5823545 | 0.74 | ALDH1A1 (0.56) | GABRA1GABRB2OPRM1OPRD1OPRK1 | |
| SCHEMBL10974173 | 0.73 | ALDH1A1 (0.49) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL15919224 | 0.73 | ALDH1A1 (0.49) | OPRK1ALDH1A1LMNAHTTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469811-B1 | Accelerators for curing phenolic resole resins | BORDEN INC (US) | 1994-11-30 | — | — | EP | claimed |
| US-5294649-A | Hardening agent of magnesioum hydroxide or lightburned magnesium oxide and promoter of a nitrogen-containing heterocyclic compound | BORDEN, INC. (US) | 1994-03-15 | — | — | US | claimed |
| EP-0469811-A2 | Accelerators for curing phenolic resole resins | Borden, Inc. (US) | 1992-02-05 | — | — | EP | claimed |