Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938489 | 0.83 | FFAR1 (0.48) | PTGESFFAR1 | |
| SCHEMBL4945455 | 0.80 | HDAC4 (0.39) | PTGESGRM5FFAR1SIGMAR1 | |
| SCHEMBL1515861 | 0.79 | MEP1A (0.46) | FFAR1FFAR4 | |
| SCHEMBL22607859 | 0.77 | FFAR1 (0.38) | PTGESGRM5FFAR1 | |
| SCHEMBL30267915 | 0.77 | FFAR1 (0.38) | PTGESGRM5FFAR1 | |
| SCHEMBL1058423 | 0.74 | CTBP2 (0.50) | SIGMAR1 | |
| SCHEMBL1515860 | 0.73 | LMNA (0.43) | SIGMAR1 | |
| SCHEMBL904249 | 0.72 | SIGMAR1 (0.57) | SIGMAR1CCR5 | |
| SCHEMBL22607856 | 0.72 | IDO1 (0.41) | SIGMAR1 | |
| SCHEMBL1707313 | 0.72 | TAAR1 (0.46) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465755-B2 | Hydrazide derivatives as prostaglandin receptors modulators | LABORATOIRES SERONO SA (CH) | 2008-12-16 | — | — | US | disclosed |
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185191-A1 | Hydrazide derivatives as prostaglandin receptors modulators | PTGIR, HPGDS, PGF | PTGES 17/4885GRM5 854/4885HAO1 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.