Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492913 | 0.92 | RAB9A (0.39) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL493213 | 0.89 | KMT2A (0.41) | ALDH1A1NPC1RAB9ACCR2KMT2A | |
| SCHEMBL493429 | 0.88 | HPGD (0.51) | HPGDKDM4EMAPTKMT2A | |
| SCHEMBL493611 | 0.86 | SMYD3 (0.43) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL493471 | 0.85 | PRCP (0.44) | NPC1RAB9ATSHRKDM4ESMYD3 | |
| SCHEMBL493504 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL493600 | 0.82 | GHSR (0.40) | NPC1RAB9ACCR2KDM4EMAPT | |
| SCHEMBL493223 | 0.82 | RAB9A (0.38) | NPC1RAB9ACCR2KDM4EMAPT | |
| SCHEMBL493820 | 0.80 | RAB9A (0.40) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL493737 | 0.80 | KMT2A (0.49) | HPGDKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |