Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493223 | 0.91 | RAB9A (0.38) | RAB9ACCR2NPC1GPR139 | |
| SCHEMBL492913 | 0.88 | RAB9A (0.39) | RAB9ACCR2NPC1ALDH1A1LIPG | |
| SCHEMBL493600 | 0.88 | GHSR (0.40) | RAB9ACCR2NPC1GPR139 | |
| SCHEMBL492929 | 0.87 | RAB9A (0.37) | RAB9ACCR2TSHRLIPGHPGD | |
| SCHEMBL493737 | 0.85 | KMT2A (0.49) | HPGD | |
| SCHEMBL494415 | 0.85 | TSHR (0.42) | RAB9ATSHRNPC1ALDH1A1HPGD | |
| SCHEMBL493779 | 0.85 | SMN1; SMN2 (0.52) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL493647 | 0.84 | KDM4E (0.48) | CCR2NPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL493863 | 0.83 | LMNA (0.48) | CCR2SMN1; SMN2 | |
| SCHEMBL494528 | 0.80 | SMN1; SMN2 (0.39) | RAB9ACCR2TSHRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |