Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494528 | 0.92 | SMN1; SMN2 (0.39) | RAB9AKMT2AKDM4EMAPTCCR2 | |
| SCHEMBL493600 | 0.90 | GHSR (0.40) | RAB9AGPR139KMT2AKDM4EMAPT | |
| SCHEMBL493223 | 0.90 | RAB9A (0.38) | RAB9AGPR139KMT2AKDM4EMAPT | |
| SCHEMBL493820 | 0.88 | RAB9A (0.40) | RAB9AGPR139CCR2ALDH1A1HPGD | |
| SCHEMBL493737 | 0.87 | KMT2A (0.49) | KMT2AKDM4EMAPTHPGD | |
| SCHEMBL493647 | 0.86 | KDM4E (0.48) | KMT2AKDM4EMAPTCCR2ALDH1A1 | |
| SCHEMBL493674 | 0.86 | TDP1 (0.38) | RAB9AKMT2AKDM4EMAPTCCR2 | |
| SCHEMBL493863 | 0.86 | LMNA (0.48) | KMT2AMAPTCCR2SMN1; SMN2 | |
| SCHEMBL494415 | 0.84 | TSHR (0.42) | RAB9AKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL493779 | 0.84 | SMN1; SMN2 (0.52) | RAB9AKMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |