Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493737 | 0.92 | KMT2A (0.49) | HPGDKMT2AKDM4EMAPT | |
| SCHEMBL493611 | 0.88 | SMYD3 (0.43) | HPGDKMT2AMAPTMEN1 | |
| SCHEMBL494528 | 0.88 | SMN1; SMN2 (0.39) | HPGDKMT2AKDM4EMAPT | |
| SCHEMBL494117 | 0.87 | HPGD (0.50) | HPGDKMT2A | |
| SCHEMBL493471 | 0.84 | PRCP (0.44) | KDM4E | |
| SCHEMBL493504 | 0.83 | SMN1; SMN2 (0.53) | HPGDKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL493213 | 0.83 | KMT2A (0.41) | KMT2A | |
| SCHEMBL494415 | 0.81 | TSHR (0.42) | HPGDKMT2AMEN1 | |
| SCHEMBL492913 | 0.80 | RAB9A (0.39) | HPGDKMT2AKDM4EMAPT | |
| SCHEMBL493677 | 0.79 | KMT2A (0.49) | HPGDKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |