Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494528 | 0.85 | SMN1; SMN2 (0.39) | NPC1RAB9ASMYD3TSHRKDM4E | |
| SCHEMBL493504 | 0.85 | SMN1; SMN2 (0.53) | NPC1RAB9ADAGLAKDM4E | |
| SCHEMBL493429 | 0.84 | HPGD (0.51) | KDM4E | |
| SCHEMBL493213 | 0.83 | KMT2A (0.41) | NPC1RAB9ASMYD3 | |
| SCHEMBL493611 | 0.82 | SMYD3 (0.43) | NPC1RAB9ASMYD3TSHR | |
| SCHEMBL493060 | 0.78 | FAAH (0.44) | PRCPNPC1RAB9AFAAHCES1 | |
| SCHEMBL493600 | 0.78 | GHSR (0.40) | NPC1RAB9AKDM4E | |
| SCHEMBL493820 | 0.77 | RAB9A (0.40) | NPC1RAB9ATSHR | |
| SCHEMBL492913 | 0.77 | RAB9A (0.39) | NPC1RAB9AKDM4E | |
| SCHEMBL494415 | 0.77 | TSHR (0.42) | NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |