Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192661 | 0.81 | HDAC9 (0.35) | MAOAMAOB | |
| SCHEMBL2028968 | 0.78 | SIGMAR1 (0.38) | — | |
| SCHEMBL6472053 | 0.76 | ACHE (0.38) | ACHE | |
| Hydrochloric Acid SCHEMBL333583 | 0.75 | ACHE (0.39) | ACHE | |
| SCHEMBL1051970 | 0.74 | MAOB (0.39) | ACHEMAOAMAOBBCHE | |
| SCHEMBL4348712 | 0.69 | MAOB (0.38) | ACHEMAOAMAOBBCHE | |
| SCHEMBL7947368 | 0.66 | MAOB (0.41) | ACHEMAOAMAOBBCHE | |
| SCHEMBL5807645 | 0.66 | KDM1A (0.40) | ACHEMAOAMAOBBCHE | |
| SCHEMBL7341859 | 0.66 | MAOB (0.38) | ACHEMAOAMAOBBCHE | |
| SCHEMBL3421261 | 0.65 | HDAC9 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956904-A2 | USE OF LOW-DOSE LADOSTIGIL FOR NEUROPROTECTION | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-08-20 | — | — | EP | claimed |
| WO-2007070425-A2 | USE OF LOW-DOSE LADOSTIGIL FOR NEUROPROTECTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-06-21 | — | — | WO | claimed |