Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 6/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL333583 | 0.99 | ACHE (0.39) | ACHECYP1A2CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL11898398 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19KMT2AKDM1A | |
| SCHEMBL16192661 | 0.77 | HDAC9 (0.35) | KMT2A | |
| SCHEMBL4946111 | 0.76 | ACHE (0.41) | ACHE | |
| SCHEMBL2028968 | 0.74 | SIGMAR1 (0.38) | CYP1A2CYP2C9CYP2C19KMT2APPARG | |
| SCHEMBL1051970 | 0.69 | MAOB (0.39) | ACHEKMT2AKDM1AMEN1 | |
| SCHEMBL4348712 | 0.66 | MAOB (0.38) | ACHEKDM1A | |
| SCHEMBL7947368 | 0.63 | MAOB (0.41) | ACHECYP1A2CYP2C9CYP2C19KDM1A | |
| SCHEMBL7341859 | 0.63 | MAOB (0.38) | ACHECYP1A2CYP2C9CYP2C19KDM1A | |
| SCHEMBL5807645 | 0.63 | KDM1A (0.40) | ACHEKMT2AKDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171210-A1 | Compositions and methods for treatment of cardiovascular disorders and diseases | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2005-08-04 | — | — | US | claimed |