Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355554 | 0.88 | MAOB (0.46) | HSD11B1ALDH1A1MAOBMAPK1TDP1 | |
| SCHEMBL8207604 | 0.75 | ALDH1A1 (0.42) | HTR2ATAAR1IDO1ALDH1A1MAOB | |
| SCHEMBL8855253 | 0.73 | PNMT (0.43) | TAAR1IDO1ALDH1A1 | |
| SCHEMBL27883878 | 0.72 | HSD11B1 (0.43) | HSD11B1TAAR1IDO1ALDH1A1MAPK1 | |
| SCHEMBL4892657 | 0.72 | HSD11B1 (0.43) | HSD11B1TAAR1ALDH1A1IKBKBDYRK2 | |
| SCHEMBL8199494 | 0.71 | MAOB (0.46) | HTR2AALDH1A1MAOBMAPK1TDP1 | |
| SCHEMBL27779232 | 0.71 | TAAR1 (0.38) | TAAR1ALDH1A1MAOBGRM2 | |
| SCHEMBL27814021 | 0.71 | TAAR1 (0.38) | HSD11B1TAAR1MAOBMAPK1GPR52 | |
| SCHEMBL27800444 | 0.71 | TP53 (0.39) | HSD11B1TAAR1ALDH1A1TDP1GPR52 | |
| SCHEMBL6231872 | 0.70 | MAOB (0.71) | HTR2ATAAR1IDO1ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |