Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ILK | Q13418 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947760 | 0.82 | APP (0.41) | MAPK8MAPK9MAPK10MGLLILK | |
| SCHEMBL4949763 | 0.82 | MAPK8 (0.41) | MAPK8MAPK9MAPK10MGLLILK | |
| SCHEMBL5596467 | 0.77 | NPC1 (0.48) | MAPK9MAPK10ILKGAARAB9A | |
| SCHEMBL7144576 | 0.74 | ILK (0.50) | MGLLILKLTA4HUSP2GAA | |
| SCHEMBL4949279 | 0.74 | MGLL (0.43) | MGLLLTA4HRAB9ANPC1MEN1 | |
| SCHEMBL5596344 | 0.74 | RAB9A (0.46) | ILKGAARAB9ANPC1MEN1 | |
| SCHEMBL5596393 | 0.73 | KDM4E (0.36) | MAPK9MAPK10ILKGAARAB9A | |
| SCHEMBL5597097 | 0.72 | PTGS1 (0.40) | ILKRAB9ANPC1PTGS1PTGS2 | |
| SCHEMBL4948519 | 0.71 | MAPK9 (0.65) | MAPK8MAPK9MAPK10LTA4HUSP2 | |
| Bentamapimod SCHEMBL2878382 | 0.71 | MAPK10 (1.00) | MAPK8MAPK9MAPK10LTA4HUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | claimed |