Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596467 | 0.81 | NPC1 (0.48) | RAB9AMAPTSMN1; SMN2CYP3A4L3MBTL1 | |
| SCHEMBL4949283 | 0.80 | ATP4A (0.41) | RAB9AMAPTSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL4949209 | 0.79 | ATP4A (0.45) | RAB9AMAPTSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL5596393 | 0.77 | KDM4E (0.36) | PTGS1PTGS2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5596344 | 0.76 | RAB9A (0.46) | RAB9AMAPTSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL4949763 | 0.73 | MAPK8 (0.41) | RAB9AMAPTSMN1; SMN2APPNPC1 | |
| SCHEMBL4948593 | 0.72 | MAPK8 (0.55) | PTGS1PTGS2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4949279 | 0.72 | MGLL (0.43) | RAB9ASMN1; SMN2KDM4ENPC1TP53 | |
| SCHEMBL4947760 | 0.72 | APP (0.41) | RAB9AMAPTSMN1; SMN2NOS1APP | |
| SCHEMBL2885027 | 0.69 | MAPK10 (0.76) | PTGS1PTGS2MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |